Etiqueta: paludismo

Three Promising Vaccine Strategies against Malaria

9. abril 2012

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Three Promising Vaccine Strategies against Malaria

Scientists inch closer to a vaccine against the mosquito-borne Plasmodium falciparum, the world’s most lethal parasite This graphic originally appeared with the article “Halting the World’s Most Lethal Parasite,” in the November 2010 issue of Scientific American. We are posting it as background for today’s announcement of good success in a phase III trial using a traditional vaccine by GlaxoSmithKline. Scroll down to see the illustration. For decades the public health community has tried to devise a vaccine that would confer lifetime immunity against the malaria parasite[...] 

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Halting the World’s Most Lethal Parasite: Immunizing Mosquitoes and Other “Crazy” Antimalaria Ideas

9. abril 2012

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Halting the World’s Most Lethal Parasite: Immunizing Mosquitoes and Other “Crazy” Antimalaria Ideas

A new malaria vaccine, a plan to immunize mosquitoes, and other “crazy” ideas have brightened prospects for vanquishing this killer By Mary Carmichael DEADLY CARGO: The Anopheles mosquito carries the malaria parasite responsible for disease and death in much of the tropics. Image: EVA-MARIA PASIEKA Corbis Right now, somewhere in the world—in a petri dish in Baltimore, maybe, or in the salivary glands of a laboratory-bred mosquito in Seattle, or in the bloodstream of a villager in Ghana—resides a chemical compound that could help eradicate human history’s biggest killer. Scientists[...] 

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When was malaria first discovered and by whom? How is the disease transmitted? What are its effects?

9. abril 2012

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When was malaria first discovered and by whom? How is the disease transmitted? What are its effects?

Image: JIM GATHANY/CDC MOSQUITO. This blood-feeding Anopheles gambiae mosquito is one of the leading malaria vectors in the world. Toby Fagan, who is currently conducting postdoctoral research on malaria at Edinburgh University, gives this response: Malaria is one of the most ubiquitous diseases known–there are more than 125 different species of malaria that infect mammals, birds and reptiles, which indicates an early origin. It has probably afflicted humans throughout our evolutionary history, although the first historical reports of symptoms that match those of malaria date back to[...] 

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What is Artemisinin?

9. abril 2012

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What is Artemisinin?

Coartem, a malaria drug whose potency is derived from a Chinese herb, may soon be approved for sale in the United States. By Jordan Lite  | December 23, 2008 DEADLY BITE The Food and Drug Administration may soon approve a drug derived from the herb artemisinin to treat malaria. Image: Public Health Image Library/James Gathany The Food and Drug Administration (FDA) is poised to decide by Friday whether to green-light the use of the malaria drug Coartem as part of an expedited review reserved for life-saving treatments that the agency believes are more effective than existing therapies. An FDA advisory[...] 

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Drug-Resistant Malaria Spreads, Scientists Hunt Down Genetic Causes

9. abril 2012

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Drug-Resistant Malaria Spreads, Scientists Hunt Down Genetic Causes

The parasite that causes malaria is becoming immune to artemisinin, the most effective drug. Pinpointing the resistance genes could offer a way to beat back the disease By Katherine Harmon  | April 5, 2012 New grounds for resistance: A camp in western Thailand, where drug-resistant malaria is becoming increasingly common Image: Timothy Anderson The malaria parasite is a wily organism, shifting its life stages as it flits from human to mosquito and back again. It still kills some 600,000 people each year and has outwitted eradication efforts, having developed resistance to previously popular drugs[...] 

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